Depression Gene Linked to Response to Stress

by Anonymous

Different people react differently to stress. Some people become angry and frustrated while others withdrawal and isolate themselves from others.

Well now there is a new study that was just published (January 3rd, 2011) in the Archives of General Psychiatry that has looked at 54 studies published between 2001 and 2010 on the role of the depression gene

An analysis of 54 studies that examined the 5-HTTLPR transported gene across 41,000 participants suggest that there is a depression gene that really affects how people respond to stressful life events.

People with a short variation of the serotonin transporter (5-HTTLPR) gene are more likely to become depressed when faced with certain stressful life events than their counterparts who have the longer variation, the new study showed.

What’s more, not all stressful life events are created equally when it comes to depression risk. For example, this gene raises risk of depression in people who have experienced stress related to childhood maltreatment and severe medical illness as opposed to other stressful events.

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